Clinical analysis of 136 cases of complete uterine rupture in late pregnancy

HONG Teng, YANG Chun-li, CUI Shi-hong, SU Dan

Chinese Journal of Practical Gynecology and Obstetrics ›› 2026, Vol. 42 ›› Issue (2) : 238-242.

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Chinese Journal of Practical Gynecology and Obstetrics ›› 2026, Vol. 42 ›› Issue (2) : 238-242. DOI: 10.19538/j.fk2026020120

Clinical analysis of 136 cases of complete uterine rupture in late pregnancy

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Abstract

Objective To analyze the causes,clinical features and common risk factors of complete uterine rupture and to reduce the impact of uterine rupture on maternal and fetal outcomes. Methods A total of 136 patients with complete uterine rupture in late pregnancy from various regions of Henan Province between January 2016 and August 2023 were retrospectively analyzed for the causes of rupture,clinical characteristics,risk factors,and maternal and infant outcomes. Results (1)The causes of uterine rupture were mainly scarred uterus after cesarean section and history of uterine operation,which accounted for 79.41% and 13.24%,respectively.(2) The main symptoms of uterine rupture were abdominal pain,abnormal fetal heartbeat,and vaginal bleeding,among which the incidence of abdominal pain was 77.94%,fetal heartbeat abnormality was 34.56%,and vaginal bleeding accounted for 21.32%.(3) Maternal and fetal outcome:136 cases of uterine rupture,83 cases had a good outcome,53 cases had an adverse pregnancy outcome,and the incidence of postpartum hemorrhage was 32.35%,of which the incidence of massive blood transfusion was 29 cases(21.32%),and hysterectomy was 14 cases,with an incidence of 10.29%. There were 0 maternal deaths. Maternal adverse pregnancy outcomes were associated with gravidity(OR=2.13,95% CI 1.08-4.20,P=0.029),and the length of uterine rupture (OR=1.21,95% CI 1.09-1.34,P<0.001),and the site of uterine rupture (OR=4.19,95% CI 1.32-13.29,P=0.015).(4) perinatal outcomes:133 cases of perinatal cases were included in this study,74 cases of adverse pregnancy outcomes,preterm labor 42 cases,34 cases of neonatal asphyxia,11 cases of intrauterine fetal death,13 cases of neonatal death,and the perinatal mortality rate was 18.05%. Adverse perinatal outcomes were associated with gestational week(OR=0.51,95%CI 0.36-0.70,P<0.001),and length of uterine rupture (OR=1.16,95% CI 1.04-1.33,P=0.031),and abnormal fetal cardiac monitoring (OR=7.16,95% CI 1.88-27.32,P=0.004). Conclusions In those with keloid uterus re-pregnancy,symptoms of persistent abdominal pain in late pregnancy and abnormal fetal heartbeat and vaginal bleeding during labor should be alerted to the possibility of uterine rupture. Scarred uterus is a major risk factor for uterine rupture. Length of uterine rupture is a risk factor for adverse maternal outcomes. Length of uterine rupture and abnormal fetal cardiac monitoring are risk factors for adverse perinatal outcomes.

Key words

uterine rupture / late pregnancy / maternal and pediatric outcomes

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HONG Teng , YANG Chun-li , CUI Shi-hong , et al. Clinical analysis of 136 cases of complete uterine rupture in late pregnancy[J]. Chinese Journal of Practical Gynecology and Obstetrics. 2026, 42(2): 238-242 https://doi.org/10.19538/j.fk2026020120

References

[1]
Nie Q, Luo S, Chen B, et al. Risk factors and outcomes of uterine rupture before onset of labor vs. during labor:a multicenter study[J]. J Perinat Med, 2025, 53(4):503-508. DOI:10.1515/jpm-2024-0309.
[2]
刘喆, 杨慧霞, 辛虹, 等. 全国多中心子宫破裂现状调查及结局分析[J]. 中华妇产科杂志, 2019, 54(6):363-368. DOI:10.3760/cma.j.issn.0529-567x.2019.06.002.
[3]
Xie J, Lu X, Liu M. Clinical analysis of complete uterine rupture during pregnancy[J]. BMC Pregnancy Childbirth, 2024, 24(1):255. DOI:10.1186/s12884-024-06394-2.
[4]
孔北华, 马丁, 段涛. 妇产科学[M]. 10 版. 北京: 人民卫生出版社,2024:238-240.
[5]
Finnsdottir SK, Maghsoudlou P, Pepin K, et al. Uterine rupture and factors associated with adverse outcomes[J]. Arch Gynecol Obstet, 2023, 308(4):1271-1278.DOI:10.1007/s00404-022-06820-w.
[6]
Vandenberghe G, Bloemenkamp K, Berlage S, et al. The International Network of Obstetric Survey Systems study of uterine rupture:a descriptive multi‐country population‐based study[J]. BJOG, 2018, 126(3):370-381. DOI:10.1111/1471-0528.15271.
[7]
Zhou Y, Mu Y, Chen P, et al. The incidence,risk factors and maternal and foetal outcomes of uterine rupture during different birth policy periods:an observational study in China[J]. BMC Pregnancy Childbirth, 2021, 21(1):360. DOI:10.1186/s12884-021-03811-8.
[8]
Hesselman S, Lampa E, Wikman A, et al. Time matters-a Swedish cohort study of labor duration and risk of uterine rupture[J]. Acta Obstet Gynecol Scan, 2021, 100 (10):1902-1909. DOI:10.1111/aogs.14211.
[9]
Vandenberghe G, Vierin A, Bloemenkamp K, et al. Incidence and outcomes of uterine rupture in women with unscarred,preterm or prelabour uteri:data from the international network of obstetric survey systems[J]. BJOG, 2023, 130(12):1493-1501.DOI:10.1111/1471-0528.17517.
[10]
Ma R, Huang L, Tuo X, et al. Outcomes of uterine rupture in unscarred compared with the scarred uterus:analysis of 61 complete uterine rupture[J]. J Matern Fetal Neonatal Med, 2025, 38(1):2505084. DOI:10.1080/14767058.2025.2505084
[11]
Arkerson BJ, Muraca GM, Thakur N, et al. Prediction of uterine rupture in singleton pregnancies with one prior cesarean birth undergoing TOLAC:A cross-sectional study. Acta Obstet Gynecol Scan, 2025, 10(1):185-193. DOI:10.1111/aogs.15009.
[12]
庄璟怡, 应豪. 妊娠期子宫破裂的早期识别[J]. 中国实用妇科与产科杂志, 2023, 39 (4):406-411. DOI:10.19538/j.fk2023040107.
[13]
Abdulmane MM, Sheikhali OM, Alhowaidi RM, et al. Diagnosis and management of uterine rupture in the third trimester of pregnancy:a case series and literature review[J]. Cureus, 2023, 15(6):e39861. DOI:10.7759/cureus.39861
[14]
中华医学会妇产科学分会产科学组. 剖宫产术后再次妊娠阴道分娩管理的专家共识(2016)[J]. 中华妇产科杂志, 2016, 51(8):561-564. DOI:10.3760/cma.j.issn.0529-567x.2016.08.001.
[15]
Zhang L, Chen L, Hong X, et al. Complete rupture of the pregnant uterus:A 12-year retrospective study[J]. Int J Gynecol Obstet, 2024, 167 (1):389-394. DOI:10.1002/ijgo.155776.
[16]
Amikam U, Hochberg A, Abramov S, et al. Risk factors for maternal complications following uterine rupture:a 12-year single-center experience[J]. Arch Gynecol Obstet, 2024, 309(5):1863-1871. DOI:10.1007/s00404-023-07061-1.
[17]
De Pinho A, Martins Dos Santos F, Carmo O, et al. Uterine rupture in pregnancy over 5 years:A retrospective descriptive study[J]. Womens Health(Lond), 2025, 21:17455057251399891. DOI:10.1177/17455057251399891.
[18]
Al-Zirqi I, Vangen S. Prelabour uterine rupture:characteristics and outcomes[J]. BJOG, 2020, 127 (13):1637-1644. DOI:10.1111/1471-0528.16363.
[19]
何津, 单延红, 沈齐. 非产时自发性子宫破裂的识别和处置[J]. 中国实用妇科与产科杂志, 2024, 40(12):1171-1176.DOI:10.19538/j.fk2024120106.
[20]
白桂芹, 陈蔚琳, 高劲松. 中孕期剖宫产瘢痕妊娠临床管理专家共识(2024年版)[J]. 中国实用妇科与产科杂志, 2024, 40(11):1108-1113.DOI:10.19538/j.fk2024110112.
[21]
文燕青, 漆洪波. 多学科团队诊疗——提高救治效果[J]. 中国实用妇科与产科杂志, 2024, 40(10):978-981.DOI:10.19538/j.fk2024100105.

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利益冲突 所有作者均声明不存在利益冲突

Funding

Joint Construction Project of Henan Provincial Department of Science and Technology(HGJ20190366)
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