Management of anemia during adjuvant therapy in patients with gynecologic malignancies

ZHOU Nian, ZHANG Guo-nan

Chinese Journal of Practical Gynecology and Obstetrics ›› 2025, Vol. 41 ›› Issue (10) : 972-975.

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Chinese Journal of Practical Gynecology and Obstetrics ›› 2025, Vol. 41 ›› Issue (10) : 972-975. DOI: 10.19538/j.fk2025100104

Management of anemia during adjuvant therapy in patients with gynecologic malignancies

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Abstract

Anemia frequently occurs in gynecologic malignancy patients undergoing adjuvant therapy,with iron-deficiency anemia (IDA) being the most prevalent. Anemia reduces patients' tolerance to treatment,leading to therapy delays,dose reductions,or even discontinuation. This may result in chemotherapy resistance and decreased radiotherapy sensitivity. Correcting anemia can improve prognosis,so standardized anemia management is essential. Common therapeutic approaches include iron supplementation,erythropoiesis-stimulating agents (ESAs),and blood transfusions. Among these,third-generation intravenous iron preparations have emerged as a new option in the anemia management in adjuvant therapy for patients with gynecological malignancies due to their rapid iron repletion,reduced transfusion risks,and the convenience of single-dose administration.

Key words

gynecologic malignancies / cancer-related anemia / chemotherapy-induced anemia / iron-deficiency anemia / intravenous iron

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ZHOU Nian , ZHANG Guo-nan. Management of anemia during adjuvant therapy in patients with gynecologic malignancies[J]. Chinese Journal of Practical Gynecology and Obstetrics. 2025, 41(10): 972-975 https://doi.org/10.19538/j.fk2025100104

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