The treatment of low-risk gestational trophoblastic neoplasia，based on the chemotherapy recommended by FIGO guidelines，should be stratified again，and actinomycin D（Act-D）or methotrexate（MTX） single-agent chemotherapy should be selected for those of 0-4 points. According to some research reports，the efficacy of Act-D is better than that of MTX，and the side effects are lower；single-agent chemotherapy is recommended for those with a score of 5-6，but the indications for combined chemotherapy can be broadened. The curative effect should be closely monitored during chemotherapy，and if the single-agent chemotherapy is resistant，another single-agent or combination regimen can be used individually.