Thyroid storm is a kind of endocrine emergency，which is characterized by rapid deterioration. Pregnancy with thyroid storm has the characteristics of low incidence and high mortality，which brings great challenge to clinical diagnosis and treatment. The occurrence of thyroid storm has clear incentives，and the diagnosis is mostly based on clinical manifestations. At present，there are several predictive models for the diagnosis of thyroid storm，but each has its advantages and disadvantages. In clinical work，a comprehensive analysis is required to strive for early and timely diagnosis，and to initiate accurate and effective treatment as soon as possible and avoid inappropriate medication，in order to improve perinatal outcome.