中国实用妇科与产科杂志

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不孕症合并慢性子宫内膜炎的诊治

  

  1. 中山大学附属第一医院生殖医学中心,广东 广州 510080
  • 出版日期:2020-06-02 发布日期:2020-05-21
  • 通讯作者: 徐艳文
  • 基金资助:
    中国博士后科学基金(2019M663282)

Diagnosis and treatment of infertile women with chronic endometritis.

  1. Center for Reproductive Medicine,Department of Obstetrics & Gynecology,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China
  • Online:2020-06-02 Published:2020-05-21

摘要: 慢性子宫内膜炎(chronic endometritis,CE)是子宫内膜受感染所致的慢性内膜炎症性疾病,临床症状轻微,但与不孕症及不良妊娠结局有密切关系。诊断CE的金标准为组织学观察到子宫内膜间质细胞间隙有浆细胞浸润。抗生素是目前治疗CE的首选方法,可能改善不孕患者的妊娠结局,但部分持续性CE患者对抗生素治疗不敏感。

关键词: 慢性子宫内膜炎, 不孕症, 浆细胞, CD138

Abstract: Chronic endometritis(CE)is an infectious and inflammatory condition of endometrium which often shows subtle clinical disturbances.CE was reported to be associated with infertility and adverse pregnancy outcomes.The golden standard for CE diagnosis was histologic finding of multiple plasmacytes infiltration in endometrial stroma.Oral antibiotic treatment was the first line treatment of CE,which may improve the pregnancy outcome,but those with persistent CE were insensitive to antibiotics.

Key words: chronic endometritis, infertility, plasmacyte, CD138

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