中国实用妇科与产科杂志
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摘要：
局部晚期宫颈癌的治疗目前有很大的争议，美国国立综合癌症网络（NCCN）指南推荐直接行放疗，但其技术问题可能会引起不可逆的相关并发症，损伤性较大，而新辅助化疗+宫颈癌手术，是目前很多国家及地区采用的治疗方案，但目前没有统一的化疗方案、用药剂量以及强度，如何筛选出对新辅助化疗不敏感的患者以制定更加合理的治疗方案，避免治疗时机的贻误，尚需大样本、随机、多中心研究结果的支持。文章就宫颈癌新辅助化疗相关问题做一综述，旨在为临床治疗提供理论基础。
关键词: 宫颈肿瘤, 新辅助化疗, 化疗方案
Abstract:
The treatment for locally advanced cervical cancer is currently controversial.NCCN recommends direct radiotherapy，but the damage is greater.Neoadjuvant chemotherapy combined with radical surgery is currently used in many countries and regions.However，there is no uniform chemotherapy regimen，dose or strength.In order to screen patients who are not sensitive to neoadjuvant chemotherapy so as to develop a more reasonable treatment regimen and avoid delay in the timing of treatment，large sample，random multicenter results are needed.This article reviews the problems related to neoadjuvant chemotherapy for cervical cancer in order to provide a theoretical basis for clinical treatment.
Key words: cervical neoplasms, neoadjuvant chemotherapy, chemotherapy regimen
中图分类号:
R737.3
赵卫东. 局部晚期宫颈癌术前化疗药物及方案的选择[J]. 中国实用妇科与产科杂志, DOI: 10.19538/j.fk2018110105.
ZHAO Wei-dong. Choice of chemotherapy regimen and medicine for locally advanced cervical cancer.[J]. Acta Metallurgica Sinica, DOI: 10.19538/j.fk2018110105.
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https://www.zgsyz.com/zgsyfck/CN/Y2018/V34/I11/1203
