中国实用妇科与产科杂志

中国实用妇科与产科杂志

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子宫腺瘤样瘤59例临床病理分析

王晨羽1，杨海峰2，罗津奇1，丁培堃1，杨思聪1，杨远忠3，李楚天2   

  1. 作者单位: 1.暨南大学医学院，广东 广州 510632；2. 广东省中医院病理科，广东 广州 510120；3. 中山大学肿瘤防治中心病理科，广东 广州 510060
  • 出版日期:2014-12-02 发布日期:2015-01-04
  • 通讯作者: 杨海峰

A clinical pathological study of adenomatoid tumors of uterus:report of 59 cases.

WANG Chen-yu**，YANG Hai-feng，LUO Jin-qi**，DING Pei-kun**，YANG Si-cong**，YANG Yuan-zhong，LI Chu-tian.   

  1. *Department of Clinical Medicine，Medical School，Jinan University，Guangzhou 510632，China
  • Online:2014-12-02 Published:2015-01-04

摘要：

目的 探讨子宫腺瘤样瘤的临床病理特点，提升子宫腺瘤样瘤的诊断水平。 方法 对广东省中医院2006年1月至2011年12月收治的59例子宫腺瘤样瘤患者的手术标本进行临床病理及免疫组织化学观察，分析其临床及病理学特征。 结果 59例子宫腺瘤样瘤患者年龄平均（39.8±8.6）岁，临床表现多样化，以月经异常为主；腺瘤样瘤直径平均（2.7±1.9）cm，多为单发，多位于子宫肌壁；多数患者合并子宫平滑肌瘤或子宫腺肌病等疾病，合并异位妊娠比例较高（7.84%）。免疫组化显示CK AE1/AE3、Vimentin、Calretinin阳性率均达到98.3%。部分病例HBME-1阳性。 结论 子宫腺瘤样瘤是一种临床和病理检查易误诊和漏诊的少见间皮源性肿瘤，临床上常与子宫平滑肌瘤等多种疾病伴发，并可能与异位妊娠的发生有因果关系。免疫组化可作为诊断和鉴别诊断的重要参考依据。

关键词: 子宫肿瘤, 腺瘤样瘤, 间皮肿瘤

Abstract:

Abstract： Objective To investigate the clinical and pathological characteristics of uterine adenomatoid tumor.Methods    The clinical information，histopathology features and immunohistochemistry results of 59 cases of uterine adenomatoid tumor were collected to study their clinical and pathological characteristics. Results    The average age of the 59 cases was 39.8±8.6 years. There were a variety of clinical symptoms in 59 cases and the principal symptom was abnormal menstruation，while most of the cases were complicated by other uterine and ovary diseases. The average diameter of uterine adenomatoid tumors was(2.7±1.9)cm .The uterine adenomatoid tumors  were positive in CK AE1/AE3,Vimentin and Calretinin with immunohistochemistry. A part of cases were HBME-1 positive. Conclusions  There’s evidence that adenomatoid tumor of uterus originates in mesothelium. Adenomatoid tumor of uterus can be misdiagnosed in clinical and pathological examination,which should be differentiated from other tumors carefully. Immunohistochemistry plays a great role in diagnosing the disease.

Key words: uterine tumors, adenomatoid tumors, mesothelial tumors

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