女性生殖道沙眼衣原体感染的诊治

doi:10.7504/fk2014080104

摘要/Abstract

摘要：

生殖道沙眼衣原体感染是最常见的性传播疾病之一，明确诊断需依据实验室检测。由于患者早期症状多不明显，而女性持续或反复感染常导致严重并发症，因而早诊断、及时有效的规范化治疗并追踪随访对患者具有十分重要的意义。近年来核酸扩增等分子生物学技术的发展和标本取材方法的改进都极大地推动了沙眼衣原体感染的筛查，目前最好的公共健康干预手段是增加筛查率和积极治疗感染者，同时不能忽视性健康教育为基础的一级预防。

关键词: 沙眼衣原体, 女性生殖道, 感染

Abstract:

Abstract: Chlamydia trachomatis infection is one of the most common sexually transmitted diseases in the world，which is mainly diagnosed according to laboratory tests.A substantial proportion of initial infections in both men and women are asymptomatic，and moreover female persistent infections or reinfections usually lead to severe complications.So early diagnosis，timely and effective standardized treatment，and regular follow-up may mean a great significance to patients.Recently，both development in nucleic acid amplification-based diagnostic tests and improvement in collecting specimens greatly promote the Chlamydia trachomatis infections screening.Currently the best public health interventions to prevent infections are to increase screening rates as well as actively provide treatment for patients，without ignoring the sexual health educations-based primary prevention.

Key words: Chlamydia trachomatis, female genital tract, infection

中图分类号:

R759

王辰，薛凤霞，韩姹. 女性生殖道沙眼衣原体感染的诊治[J]. 中国实用妇科与产科杂志, DOI: 10.7504/fk2014080104.

WANG Chen,XUE Feng-xia,HAN Cha.. Diagnosis and treatment for Chlamydia tracho- matis infection in female genital tract.[J]. Acta Metallurgica Sinica, DOI: 10.7504/fk2014080104.

参考文献

［1］   Geneva: World Health Organization; 2011.Global prevalence and incidence of selected curable sexually transmitted diseases: Overview and estimates.

［2］   郑冰洁,尹跃平.泌尿生殖道沙眼衣原体感染的流行病学进展［J］.国际皮肤性病学杂志，2011，3:183-186.

［3］   Malhotra M，Sood S，Mukherjee A，et al.Genital Chlamydia trachomatis: an update［J］.Indian J Med Res，2013,138(3):303-316.

［4］   Centers for Disease Control and Prevention.Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neisseria gonorrhoeae，2014［J］.MMWR Recommendations and Reports，2014,63( RR-2):1-14.

［5］   Centers for Disease Control and Prevention.Sexually transmitted diseases treatment guidelines，2010［J］.MMWR Recommendations and Reports,2010,59(RR-12) :1-110.

［6］    刘朝晖,薛凤霞.黏液脓性宫颈炎的诊断和治疗［J］.中国实用妇科与产科杂志,2012,4:241-242.

［7］    Mourad A，Sweet RL，Sugg N，et al.Relative resistance to erythromycin in Chlamydia trachomatis［J］.Antimicrob Agents Chemother，1980,18(5):696-698.

［8］    Jones RB，Van der Pol B，Johnson RB.Susceptibility of Chlamydia trachomatis to trovafloxacin［J］.J Antimicrob Chemother，1997,39（Suppl B）:63-65.

［9］    Somani J，Bhullar VB，Workowski KA，et al.Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure［J］.J Infect Dis，2000,181(4):1421-1427.

［10］   Gomberg MA.Combined treatment of persisting urogenital chlamydia infection with sumamed and interferon alfa ［J］.Antibiot Khimioter，2002,47(5):12-15.

［11］   American College of Obstetricians and Gynecologists.ACOG Practice Bulletin No.121.Long-acting reversible contraception: Implants and intrauterine devices［J］.Obstet Gynecol，2011,118(1):184-196.

［12］    Caddy S，Yudin MH，Hakim J，et al.Best practices to minimize risk of infection with intrauterine device Insertion［J］.J Obstet Gynaecol Can，2014,36(3):266-276.

［13］    Hocking JS，Guy R，Walker J，et al.Advances in sampling and screening for chlamydia［J］.Future Microbiol，2013,8(3):367-386.

（2014-05-26收稿）

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