子宫颈低级别鳞状上皮内病变（LSIL）是一种继发于急性HPV感染的组织学改变，总体预后良好。在排除更严重病变的前提下，LSIL的处理原则以随访为主。但对于既往细胞学结果为不能排除高级别鳞状上皮内病变不典型鳞状细胞（ASC-H）、高级别鳞状上皮内病变（HSIL）的LSIL，需注意排除隐匿性HSIL，必要时诊断性锥切以减少误诊。持续性或反复性LSIL的处理应综合评估，制定个体化方案。

Low-grade cervical squamous intraepithelial lesion （LSIL） is a histological change secondary to acute HPV infection，with a good overall prognosis.Under the precondition of excluding more serious lesions，the management of LSIL is mainly follow-up.However，for LSIL with previous cytological results of ASC-H and HSIL，concealed HSIL should be excluded，and if necessary，diagnostic conization is recommended to reduce misdiagnosis.The individualized treatment for persistent or recurrent LSIL should be made after comprehensive evaluation.