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PDF(890 KB)
PDF(890 KB)
妊娠期甲状腺功能亢进综合征的诊治
妊娠期甲状腺功能亢进综合征是妊娠早期常见的甲状腺功能异常。该病与妊娠早期血绒毛膜促性腺激素升高和促甲状腺激素(TSH)相应改变有关。伴随着怕热、多汗、情绪不稳、呕吐、心悸等临床症状。实验室检查TSH降低,游离甲状腺素(FT4)和总甲状腺素(TT4)增加,甲状腺过氧化物酶抗体(TPOAb)、甲状腺球蛋白抗体(TgAb)和促甲状腺激素受体抗体(TRAb)阴性。治疗以对症支持治疗为主,不建议使用抗甲状腺药物。
Abstract:Gestational hyperthyroidism is a common thyroid dysfunction during early pregnancy. The cause of the gestational hyperthyroidism is believed to be a result of cross- reactivity between HCG and TSH at the thyroid receptor. Women with this disease have heat intolerance, sweating, mood swings, vomiting, heart palpitations and other symptoms. Serum TSH is frequently low and FT4 is high, and autoimmuantibodys are negative. Supportive therapy is recommended, while ATDs are not recommended.
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