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多囊卵巢综合征流行病学研究
多囊卵巢综合征(polycystic ovary syndrome, PCOS)是育龄妇女最常见的内分泌紊乱性疾病之一，我国育龄妇女患病率5.6%，也是引起无排卵性不孕的主要原因。PCOS以月经紊乱、多毛、不孕、高雄激素症等为主要表现，易发生胰岛素抵抗、高胰岛素血症、2型糖尿病(diabetes mellitus, T2DM)（非胰岛素依赖型）、高血脂、心血管疾病、代谢综合征、睡眠窒息、非酒精性脂肪肝、妊娠期糖尿病和妊娠期高血压疾病等，PCOS患病率与不同种族、地区、调查对象和诊断标准有关，大多数文献报道其患病率在5%～10%。
Abstract:Polycystic ovary syndrome (PCOS) is a common metabolic dysfunction and heterogeneous endocrine disorder in women of reproductive age.PCOS is characterized by a clustering of hyperandrogenism, hyperinsulinemia, hypersecretion of LH, menstrual dysfunction, hirsutism, infertility and pregnancy and neonatal complications. PCOS also contributes to other long-term health risks, metabolic complications and psychological problems, such as type II diabetes mellitus (DM2), cardiovascular disease (CVD), poor self-esteem, venous thromboembolism (VTE) and anxiety. In addition, a wide range in the incidence of PCOS has been reported in small samples from different countries. As a result, most studies quoted a prevalence of PCOS ranging from 5% to 10%. However, previous reports from a variety of different countries demonstrate the diversity in the incidence of PCOS, and the prevalence of PCOS also depends on the criteria used to evaluate this syndrome. Different PCOS prevalence surveys have been carried out in specific populations using special diagnostic criteria.
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