PDF(916 KB)
PDF(916 KB)
PDF(916 KB)
美国妇产科医师学会及美国生殖医学会“与年龄相关的女性生育力减退共识”解读
女性的生育力随着年龄的增加逐渐下降,尤其在32岁之后下降明显,37岁之后生育力下降更迅速。对于有生育要求的女性,加强教育以及提高其年龄对生育力影响的意识是非常关键的。鉴于随着年龄增加生育力下降、损害女性生育力的疾病发病率增加以及妊娠丢失的风险增高,年龄>35岁的女性应该在超过6个月试孕失败的情况下得到快速的评价并接受治疗。年龄>40岁的女性更应该及时接受评价和治疗。
women / age / fertility / American College of Obstetricians and Gynecologists (ACOG) / American Society for Reproductive Medicine
[1] Baker TG. A quantitative and cytological study of germ cells in human ovaries[J]. Proc R Soc Lond B Biol Sci,1963,158:417-433.
[2] Block E. Quantitative morphological investigations of the follicular system in women; variations at different ages[J]. Acta Anat (Basel) 1952,14:108-123.
[3] Faddy MJ, Gosden RG, Gougeon A, et al.Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause[J]. Hum Reprod,1992;7:1342-1346.
[4] Broekmans FJ, Kwee J, Hendriks DJ, et al. A systematic review of tests predicting ovarian reserve and IVF outcome[J]. Hum Reprod Update, 2006,12:685-718.
[5] Simpson JL. Genetic programming in ovarian development and oogenesis[A]. In: Lobo RA, Kelsey J, Marcus R, editors. Menopause: biology and pathology[M]. San Diego (CA): Academic Press,2000:77-94.
[6] Balasch J, Gratacos E. Delayed childbearing: effects on fertility and the outcome of pregnancy[J]. Curr Opin Obstet Gynecol,2012,24:187-193.
[7] Battaglia DE, Goodwin P, Klein NA, et al. Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women[J]. Hum Reprod,1996,11:2217-2222.
[8] Pellestor F, Andreo B, Arnal F, et al. Maternal aging and chromosomal abnormalities: new data drawn from in vitro unfertilized human oocytes[J]. Hum Genet,2003,112:195-203.
[9] Munne S, Alikani M, Tomkin G, et al.Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities[J]. Fertil Steril,1995,64:382-391.
[10] Farr SL, Schieve LA, Jamieson DJ. Pregnancy loss among pregnancies conceived through assisted reproductive technology, United States, 1999-2002[J]. Am J Epidemiol,2007,165:1380-1388.
[11] Centers for Disease Control and Prevention, American Society for Reproductive Medicine Society for Assisted Reproductive Technology. 2010 assisted reproductive technology: fertility clinic success rates report[M]. Atlanta (GA): CDC,2012:1.
[12] Schwartz D, Mayaux MJ. Female fecundity as a function of age: results of artificial insemination in 2193 nulliparous women with azoospermic husbands. Federation CECOS[J]. N Engl J Med,1982,306:404-406.
[13] Cohen MA,Chang PL,Uhler M,et al. Reproductive outcome after sterilization reversal in women of advanced reproductive age [J]. J Assist Reprod Genet,1999,16(8):402-404.
(2015-04-10收稿 2015-05-18修回)
/
| 〈 |
|
〉 |