从DOHaD理论看孕期营养干预的重要性

李婷; 段涛

doi:10.7504/fk2014070102

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中国实用妇科与产科杂志 ›› 2014, Vol. 30 ›› Issue (8) : 582-585. DOI: 10.7504/fk2014070102

述评

从DOHaD理论看孕期营养干预的重要性

李婷，段涛

作者信息 +

Importance of intervening the nutritional problems during pregnancy in based on evidences of developmental origins of health and disease (DOHaD).

LI Ting,DUAN Tao.

Author information +

文章历史 +

摘要

孕期可能出现多种营养问题。与健康和疾病发育起源学说(DOHaD)的相关研究显示，妊娠期热量摄入过多或过少、三大营养素水平失衡以及包括铁、叶酸在内的多种微量营养素缺乏，都可以通过改变胎儿下丘脑-垂体-肾上腺素轴应答、氧化应激状态、表观遗传学等机制，永久的改变后代对疾病的易感性，增加成年期慢性疾病的发生。产科医生需根据循证医学证据，在孕期对所有孕妇实施合理的营养干预，提高整个人群的健康素质。

Abstract

Abstract: Pregnancy women may facing various nutritional problems during pregnancy including excess or insufficient energy intake, imbalance of macronutrients, deficiency of micronutrient . Based on evidences of developmental origins of health and disease (DOHaD), the fetal hypothalamic - pituitary - adrenaline-axis response, oxidative stress and epigenetic mechanisms can be permanently changed by these nutritional problems. The susceptibility to chronic non-communicable disease in adulthood is changed. Obstetricians should intervene the nutritional problems based on uptodate evidences to improve the health of the whole population.

导出引用

李婷，段涛. 从DOHaD理论看孕期营养干预的重要性[J]. 中国实用妇科与产科杂志. 2014, 30(8): 582-585 https://doi.org/10.7504/fk2014070102

LI Ting,DUAN Tao.. Importance of intervening the nutritional problems during pregnancy in based on evidences of developmental origins of health and disease (DOHaD).[J]. Chinese Journal of Practical Gynecology and Obstetrics. 2014, 30(8): 582-585 https://doi.org/10.7504/fk2014070102

中图分类号： R714.2

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（2014-04-28收稿）