中国实用妇科与产科杂志

中国实用妇科与产科杂志

• 专题笔谈 • 上一篇    下一篇

染色体异常与自然流产

  

  1. 山东大学附属生殖医院，山东 济南 250012
  • 出版日期:2020-11-02 发布日期:2020-11-10
  • 通讯作者: 颜军昊
  • 基金资助:
    国家重点研发计划（2018YFC1002804）

Chromosome abnormality and spontaneous abortion

  1. Reproductive Hospital Affiliated to Shandong University，Jinan 250012，China
  • Online:2020-11-02 Published:2020-11-10

摘要： 染色体异常是自然流产的常见原因，包括夫妇染色体异常和胚胎染色体异常。其中夫妇染色体异常涉及结构异常，如相互易位、罗氏易位、倒位等；数目异常，如特纳综合征、克氏综合征等。胚胎染色体异常以非整倍体为主。文章将对染色体异常与自然流产的相关研究进展予以阐述。

关键词: 染色体异常, 自然流产, 植入前遗传学检测

Abstract: Embryonic chromosomal abnormalities are common reasons of spontaneous abortions，and the main abnormalities of which are aneuploidies.Some embryonic chromosomal abnormalities are due to the fact that one or both of the parents are chromosomal rearrangement carriers，including structural rearrangements such as reciprocal balanced translocations，Robertsonian translocations and inversions，or numerical rearrangements such as Triple X syndrome（47，XXX）and Double Y syndrome（47，XYY）.This article focuses on the research progress in the relationship between chromosomal abnormalities and spontaneous abortion.

Key words: chromosomal abnormalities, spontaneous abortion, preimplantation genetic testing

中图分类号: