关键词: 特发性癫痫, 枕叶癫痫, 脑电图, 偏头痛

Abstract: Objective　To characterize the clinical features and electroencephalographic （EEG） features of childhood occipital epilepsy of Gastaut （COE-G）. Methods　The clinical and EEG characteristics of 7 children who were diagnosed as COE-G were identified and followed-up clinically， with sleep and awake EEGs. Results　COE-G had a peak age of onset at about 9 years. Visual manifestations were the most common ictal event. Ictal deviation of the eyes associated with ipsilateral turning of the head and migraine-like symptoms were frequent. Hemiconvulsions occurred in 3 children， and only one child had secondarily generalized tonic-clonic seizures （GTCS）. In all patients the seizures occurred while awake， and 2 also had seizures during sleep. EEG showed that the majority of the patients had occipital spike-wave discharges when the eyes were closed, which disappeared when the eyes were open. One child continued having frequent seizures despite antiepileptic drugs treatment and two cases had subtle cognitive deficits. Conclusion　COE-G， a late onset childhood occipital seizures， is a distinctive epilepsy syndrome， and sheds some doubts on the prognosis and longterm evolution.

Key words: electroencephalography, migraine , occipital seizures