中国实用儿科杂志

中国实用儿科杂志

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早产儿囊性脑室周围白质软化症与低碳酸血症及机械通气关系

王卫，刘晓红，林英   

  1. 深圳市儿童医院NICU，广东深圳518026
  • 收稿日期:2006-05-20 修回日期:2006-09-10 出版日期:2007-01-06 发布日期:2007-01-06

Relation of hypocarbia and ventilation to cystic periventricular leukomalacia (cPVL) in preterm infant.

WANG Wei,LIU Xiaohong,LIN Ying.   

  1. Shenzhen Children’s Hospital,Shenzhen 518026,China
  • Received:2006-05-20 Revised:2006-09-10 Online:2007-01-06 Published:2007-01-06

摘要： 摘要】目的探讨早产儿囊性脑室周围白 质软化症(cPVL)与低碳酸血症及机械通气的关系。方法比较cPVL与非cPVL早产儿(各10例)生后3d内发生的低碳酸血症(至少2次PaCO2<3.33kPa) 情况以及每天机械通气参数，两组在胎龄、出生体重、性别及临床情况方面统计均无差异。结果cPVL组发生低碳酸血症几率为70%，明显高于非 cPVL组的20%(P=0.02)，而两组每天机械通气参数无差异。结论早产儿cPVL的发生与低碳酸血症有关，似乎与过度通气无关。

关键词: 早产儿, 囊性脑室周围白质软化病, 低碳酸血症

Abstract: AbstractObjectiveTo study the relationship between cystic periventricular leukomalacia (cPVL) in preterm infant and hypocarbia and mechanical ventilation.MethodsThe proportion of hypocarbia in postnatal three days and parameters of ventilator everyday in cPVL group were compared with non cPVL,and no statistical difference of gestation age,birth weight and clinical conditions were found in both groups.ResultsThe ratio of hypocarbia in cPVL group (70%) was significantly higher than that in noncPVL group (20%).However,the parameters of ventilator in both groups were the same.ConclusioncPVL of preterm infant is related to hypocarbia and appeared independent of excessive ventilation.

Key words: Cystic periventricular leukomalacia, Hypocarbia