中国实用儿科杂志

中国实用儿科杂志

• 论著 • 上一篇    下一篇

睡眠呼吸暂停低通气综合征患儿的肺功能变化及其预测价值

陈晓颖，黄敬孚   

  1. 天津市儿童医院，天津300074
  • 收稿日期:2006-02-20 修回日期:2006-05-26 出版日期:2006-08-06 发布日期:2006-08-06

The change and predictive value of pulmonary function of sleep apnea hyperpnoea syndrome in children.

Chen Xiaoying,Huang Jingfu.   

  1. Tianjin Children’s Hospital,Tianjin 300074,China
  • Received:2006-02-20 Revised:2006-05-26 Online:2006-08-06 Published:2006-08-06

摘要： 目的观察临床具有鼾症和睡眠障碍病史、拟诊为睡眠呼吸暂停低通气综合征(SAHS)患儿的肺功能变化及其对多导睡眠图(PSG)结果的预测价值。 方法36例患儿经整夜的多导睡眠图监测，计算出呼吸紊乱指数(AHI)、呼吸暂停指数(AI)、低通气指数(HI)；对所有患儿行日间肺功能检测(脉冲振荡法IOS)，检测通气功能及气道阻抗等多个参数。将PSG阳性结果组和PSG阴性结果组患儿的多个肺功能参数应用统计学软件作分析比较，并用多元线性回归及Logistic回归分析AHI与肺功能参数的依赖关系。 结果两组患儿气道阻抗(R5)和1秒用力呼气容积/最高呼气流量(FEV1/PEF)差异有显著性。PSG阳性组的R5及FEV1/PEF明显升高，治疗后有不同程度改善。应用Logistic分析得出回归方程Log it(P)=-12.03446-0.535244×R5+5.797626×FEV1/PEF。即应用R5和FEV1/PEF可以推算出患儿出现PSG阳性结果的概率。 结论可以考虑将肺功能作为儿童SAHS的辅助检查方法之一，尤其是PSG检查前的筛查及对PSG阳性结果的预测，以探讨简便经济的筛查方法。

关键词: 睡眠呼吸暂停低通气综合征, 肺功能, 多导睡眠图

Abstract: AbstractObjectiveTo investigate the change and predictive value of pulmonary function of sleep apnea hyperpnoea syndrome in children. MethodsOvernight PSG was conducted on 36 snorers with suspected SAHS.Defined PSG(+) was used as an apneahyperpnoea index (AHI)≥5 and LSaO2<0.90,ΔSaO2＞0.03.All patients with snoring and sleep apnea were evaluated pulmonary function by impulse oscillation technique (IOS).Comparison of the two groups according to the AHI was done by multiple regression and logistic regression analysis. ResultsIn the 36 cases with suspected SAHS,23 were found to have SAHS.R5 and FEV1/PEF were significantly different in two groups.(P<0.05).R5 and FEV1/PEF were used to develop a model for predicting the probability (P) of having PSG positive for SAHS.Log it (P)=-12.03446-0.535244×R5+5.797626×FEV1/PEF. ConclusionBased on our study,pulmonary function can serve as a preliminary screening method and it has reference value to clinical diagnoses.

Key words: Pulmonary function, Polysomnography