中国实用儿科杂志

中国实用儿科杂志

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儿童原发性干燥综合征并发慢性萎缩性胃炎1例并文献复习

李凡，宋红梅，李正红，孙秀静，董梅，魏珉   

  1. 中国医学科学院中国协和医科大学北京协和医院儿科，北京100730
  • 收稿日期:2006-09-15 修回日期:2007-01-02 出版日期:2007-05-06 发布日期:2007-05-06

Case report of primary Sjgren's syndrome complicated with chronic atrophic gastritis in children and literature review.

LI Fan,SONG Hong-mei,LI Zheng-hong,et al.   

  1. Peking Union Medical College Hospital,Beijing 100730,China
  • Received:2006-09-15 Revised:2007-01-02 Online:2007-05-06 Published:2007-05-06

摘要： 目的提高对儿童原发性干燥综合征(pSS)并发慢性萎缩性胃炎(CAG)的认识。 方法报告北京协和医院儿科收治1例儿童pSS并发CAG的病例,并复习相关文献。 结果儿童pSS亦可并发CAG，而部分CAG可发生癌变，因此确诊CAG后应及时治疗并定期随访。对于胃镜组织病理学检查呈重度肠上皮化生和不典型增生者，应考虑手术切除。 结论对于儿童pSS内脏受累应加强认识，争取早期诊断，及时进行治疗，以改善预后。

关键词: 儿童, 原发性干燥综合征, 慢性萎缩性胃炎

Abstract: AbstractObjectiveTo recognize the children primary Sjgren's syndrome(pSS) complicated with chronic atrophic gastritis(CAG). MethodsReport one case of children(pSS) complicated with CAG,and review the related literature. ResultspSS in children could also be complicated with CAG as in adults,which could become arcinogenesis,so it could be treated immediately after establishing the diagnosis,then regular follow-up should be performed.If serious intestinal metaplasia and atypical hyperplasia were observed by gastroscopic histopathology,surgical resection should be considered. ConclusionIt is important to emphasize the recognition of children pSS with the splanchna such as stomach.Early diagnosis and treatment may improve the prognosis.

Key words: Primary Sjgren's syndrome, Chronic atrophic gastritis