关键词: 感染性心内膜炎, 并发症, 儿童

Abstract: AbstractObjectiveTo research into the clinical characteristics,therapeutic approach and in children with infectious endocarditis. MethodsClinical data of 174 children patients with IE treated in Xiangya Second Hospital of Central South University from 1980 to 2004 were reretrospectively analyzed. Results1.There are 99 patients resulting from congenital cardiovascular diseases,35 patients from rheumatic heart disease,35 patients from heart diseases without parenchymal,4 patients after operation of congenital cardiovascular diseases and 1 patient from hypertrophic cardiomyopathy (HCM).2.Clinical manifestations were: fever(86%)，hepatomegaly(425%)，splenomegaly(316%)，anaemia(374%)，erythrosedimentation faster(391%) and multiple organ embolism(178%)and 76 patients’ germiculture was positive,the rate being 4367%,and 55 patients resulted from staphylococci.3.The most concerned heart valve was diopathic mitral valve echocariogram witch,covering 483%.4.The most common complication of IE was intractable heart failure(252%),the second being nervous system complication(132%).5.Because the clinical manifestation of IE was not typical,the cases were often misdiagnosised as influenza,pneumonophthisis,acute rheumatic fever,glomerular nephritis and others.6.The cure rate of IE was 609%,among which,76 patients were cured simply by antibiotics (716%) and 30 patients were cured by antiinfection combining operation(283%);28 patients died.Cerebral embolism and intractable heart failure were common death causes in IE. ConclusionCongenital cardiovascular diseases is in the first place in the basic heart diseases,and rheumatic heart disease is decreasing gradually.Hemoculture and echocardiogram are helpful for the diagnosis of IE.The most important measure is antibiotics.The children patients should turn to surgical therapy if the medical curative effect isn t satisfactory.

Key words: Children , Complication