中国实用儿科杂志

中国实用儿科杂志

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重庆医科大学儿童医院急性呼吸道感染住院患儿病毒病原学分析

王莉佳,刘恩梅,赵晓东,蒋利萍,罗晓菊,杨锡强   

  1. 重庆医科大学儿童医院免疫研究室(400014)
  • 收稿日期:2005-05-09 修回日期:2005-09-05 出版日期:2005-12-25 发布日期:2005-12-25

Analysis of virus pathogens in children hospitalized with acute respiratory infection in Chongqing Children's Hospital.

Wang Lijia,Liu Enmei,Zhao Xiaodong,et al.   

  1. Children’s Hospital,Chongqing University of Medical Sciences,Chongqing 400014,China.
  • Received:2005-05-09 Revised:2005-09-05 Online:2005-12-25 Published:2005-12-25

摘要： 目的分析住院急性呼吸道感染(ARI)患儿病毒病原检测结果，为临床儿童急性呼吸道感染提供病毒病原学诊断依据。 方法选择2003年4月至2005年3月重庆医科大学儿童医院呼吸内科住院治疗的急性呼吸道感染患儿，取其鼻咽分泌物做免疫荧光检测筛查7种常见呼吸道病毒抗原，包括呼吸道合胞病毒(RSV)、腺病毒、流感病毒A及B型、副流感病毒Ⅰ、Ⅱ、Ⅲ型，对检测标本阳性的病例进行统计分析。 结果1052份标本中，阳性标本409份，占3888%。其中RSV阳性标本360份，占总阳性标本例数的8802%，副流感病毒Ⅲ37份占905%；RSV发病高峰时期在12月至次年2月和7、8月两个时期；RSV感染多见于3岁以下，发病高峰年龄为2~6个月，男女发病比例为224∶1。 结论2003~2005年重庆地区急性呼吸道感染的病毒病原体仍以RSV为主。

关键词: 急性呼吸道感染, 病毒病, 原学

Abstract: AbstractObjectiveTo analyse the virus pathogens that caused children hospitalized with acute respiratory infection in Chongqing from 2003 to 2005. MethodsThe 7 common respiratory viruses,including respiratory syncitial virus (RSV),adenovirus,influnenza A and B,and parainfluenza 1,2,3,were detected by using immunofluenscence viral antigen rapid diagnosis in nasopharyngeal aspirate (NPS) of children with acute respiratory infection. ResultsIn totally 1052 samples,3888% (409/1052) was shown to be viral positive.360 samples were RSV positive and 37 samples were parainfluenza 3 positive.The peak season of RSV infection was between December and February.Another epidemiological season might in July and August.Most of RSV infection cases were less than 3 years old.The ratio of male to female was 2∶1. ConclusionRSV is the most common viral pathogen in children hospitalized with acute respiratory infection in Chongqing from 2003 to 2005.

Key words: Etiology , Virus