中国实用儿科杂志

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儿童阻塞性睡眠呼吸暂停综合征对耳蜗功能影响的研究

刘大波,罗仁忠,陈倩,钟建文,周丽枫   

  1. 广州市儿童医院耳鼻咽喉科(510120)
  • 收稿日期:2005-10-10 修回日期:2005-11-01 出版日期:2005-12-25 发布日期:2005-12-25
  • 通讯作者: 刘大波

Effect of obstructive sleep apnea syndrome on cochlear function in children.

Liu Dabo,Luo Renzhong,Chen Qian,et al.   

  1. Guangzhou Children's Hospital,Guangzhou 510120,China
  • Received:2005-10-10 Revised:2005-11-01 Online:2005-12-25 Published:2005-12-25
  • Contact: Liu Dabo

摘要: 目的探讨儿童阻塞性睡眠呼吸暂停综合征(OSAS)对耳蜗功能的影响。 方法将2002年6月至2003年8月广州市儿童医院收治的26例(52耳)OSAS患儿的畸变产物耳声发射(DPOAE)的结果与28例(56耳)正常儿童DPOAE结果进行比较。 结果26例OSAS患儿多导睡眠图(PSG)示最低血氧饱和度(5791±1861),呼吸紊乱指数(2910±2331),与正常儿童相比差异均有显著性意义。OSAS患儿F1~F4频率段DPOAE反应幅值与正常组比较,差异无显著性意义(P>005);F4~F11频率段的DPOAE反应幅值及F1~F11频率段DPOAE检出率均较正常儿童低,差异有显著性意义(P<005)。 结论OSAS能导致患儿耳蜗功能受损,对OSAS患儿应常规做耳声发射检查,做到早诊断、早治疗。

关键词: 阻塞性睡眠呼吸暂停, 儿童, 耳蜗

Abstract: AbstractObjectiveTo explore the effect on cochlear function of pediatric obstructive sleep apnea syndrome(OSAS). MethodsFrom June 2002 to August 2003,distortionproduct otoacoustic emissions(DPOAE) were recorded in 26 obstructive sleep apnea patients (study group) and 28 controls. ResultsThe mean SaO2 of study group was 5791±1861 and the apneahypapnea index was 2910±2331.The amplitudes of DPOAE between F4~F11 and the prevalence of DPOAE between F1~F11 in study group were lower than those in controls,and the difference was significant (P<005). ConclusionCochlear function may be affected in pediatric patients with OSAS.Otoacoustic emissions should be a regular examination in pediatric patients with OSAS.

Key words: Children, Cochlear