Acta Metallurgica Sinica

    Next Articles

Research on identification of high-risk obesity.

JI MingZOU Da-jin.   

  1. Department of Endocrinology,Changhai Hospital,Shanghai 200433,China
  • Online:2014-10-01 Published:2014-09-30

“高危”肥胖的识别与研究

季明邹大进   

  1. 作者单位:第二军医大学附属长海医院内分泌科,上海 200433
  • 通讯作者: 邹大进
  • 作者简介:邹大进,主任医师、教授、博士生导师,第二军医大学长海医院内分泌科主任。兼任中华医学会糖尿病学分会副主任委员,中国医师协会内分泌代谢医师分会副会长,解放军内分泌专业委员会副主任委员,上海医学会糖尿病学会副主任委员,上海市疾控中心慢病控制专家组委员,上海市肥胖病防治专家组副主任;《中华糖尿病杂志》副总编辑,《中华内分泌代谢杂志》编委。
  • 基金资助:

    国家自然科学基金(81070619,81170738)

Abstract:

Abstract:Obesity is not only influenced by hereditary factors,but also complicated with disturbances of free fatty acid metabolism.It is closely related to abnormal levels of many adipokines and note,high-risk obesity is intimately correlated with Non Alcoholic Fatty Liver Disease(NAFLD),hypertriglyceridemia,hyperinsulinemia,Obstructive Sleep Apnea Syndrome (OSAS)and Polycystic Ovarian Syndrome (PCOS).Early identification of the clinical characterisitic of high-risk obesity and timely prevention could yield good results.

Key words: high risk of obesity, pathogenesis

摘要:

肥胖既存在遗传基因的影响,也存在游离脂肪酸的代谢紊乱,肥胖还与诸多脂肪细胞因子的水平异常特别是高危肥胖与非酒精性脂肪肝、高三酰甘油血症、高胰岛素血症、睡眠呼吸暂停综合征和多囊卵巢综合征关系密切。及早鉴别“高危”肥胖的临床表型特征,及时采取预防措施可取得较好效果。

关键词: 高危肥胖, 发病机制

CLC Number: