中国实用口腔科杂志

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羟磷灰石颗粒体外堆压间隙显微CT研究

陈筑苏a吴王喜b,周    磊c   

  1. 南方医科大学附属口腔医院 广东省口腔医院a牙体牙髓科,b种植中心,c, 种植中心,广州  510280
  • 出版日期:2015-02-15 发布日期:2015-04-09
  • 基金资助:

    广东省卫生厅广东省医学科学技术研究基金项目(A2013095)

CHEN Zhu-suWU Wang-xiZHOU Lei   

  • Online:2015-02-15 Published:2015-04-09

摘要:

目的    通过显微CT体外评价,比较3种不同直径羟磷灰石颗粒外部间隙分布情况,探讨材料外部间隙对临床运用的影响。方法    2014年3—4月于广州科学城显微CT实验室对颗粒直径分别为0.25 ~ 1 mm、0.4 ~ 1 mm、1 ~ 2 mm的3种人工骨材料进行体外固定,采用显微CT扫描,评价各自的间隙排列。结果    1 ~ 2 mm组羟基磷灰石颗粒压实堆积后显微CT下显示材料颗粒排列松散,颗粒团块间存在较大空隙,间隙率为61.75%;0.25 ~ 1 mm和0.4 ~ 1 mm组材料颗粒排列较为均匀,颗粒团块间存在间隙较小,间隙率分别为27.33%和42.44%。结论    显微CT可用于颗粒移植材料的微观物理参数评估,0.25 ~ 1 mm组羟磷灰石颗粒压实后颗粒团块内部排列紧密,临床上有利于植骨后稳定成骨空间。

关键词: 显微CT, 骨移植, 颗粒, 间隙, 羟磷灰石

Abstract:

Objective    To evaluate the distribution of the space between hydroxyapitite particle from 3 types of sizes by Micro-CT and the clinical effect. Methods    From March to April 2014,Micro-CT laboratory,Guangzhou Scientific City,Micro-CT scanning was performed for 3 different diameters of hydroxyapitite particle,0.25 ~ 1 mm,0.4 ~ 1 mm,1 ~ 2 mm respectively by packed in vitro. Results    Group 1 ~ 2 mm particle showed loose and irrregular distribution,the space rate 61.75%;groups 0.25 ~ 1 mm and 0.4 ~ 1 mm showed uniform and compact distribution,the space rate 27.33% and 42.44%. Conclusion    Micro-CT is a practical method for studying graft material partical;group 0.25 ~ 1 mm is fit for clinic for its uniform and compact distribution.

Key words: micro-CT, bone graft, particle, space, hydroxyapitite