[1] Leung LK,Su Y,Chen R,et al. Theaflavins in black tea and catechins in green tea are equally effective antioxidant [J]. J Nutr,2001,131(9):2248-2251.[2] 李大祥,杨荣俊,方世辉,等. Roberts法和RP2HPLC法测定茶黄素的比较研究[J]. 安徽农业大学学报,2006,33(1):87-89.[3] 沈丽萍. 茶黄素研究进展[J]. 中国农学通报,2010,26(1):134-139.[4] Lee MJ,Lambert JD,Prabhu S,et al. Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract [J]. Cancer Epidemiol Biomarkers Prev,2004,13(1):132-137.[5] Sirk TW,Friedman M,Brown EF. Molecular binding of black tea theaflavins to biological membranes: relationship to bioactivities [J]. J Agric Food Chem,2011,59(8):3780-3787. [6] Mulder TP,van Platerink CJ,Wijnand Schuyl PJ,et al. Analysis of theaflavins in biological fluids using liquid chromatography-electrospray mass spectrometry [J]. J Chromatogr B Biomed Sci Appl,2001,760(2):271-279. [7] 樊明文. 牙体牙髓病学[M]. 4版. 北京:人民卫生出版社,2012:17-26.[8] Linke HA,LeGeros RZ. Black tea extract and dental caries formation in hamsters [J]. Int J Food Sci Nutr,2003,54(1):89-95.[9] Touyz LZ,Amsel R. Anticariogenic effects of black tea(Camellia sinensis)in caries prone-rats [J]. Quintessence Int,2001,32(8):647-650. [10] Naderi NJ,Niakan M,Kharazi Fard MJ,et al. Antibacterial activity of Iranian green and black tea on streptococcus mutans:an in vitro study [J]. J Dent(Tehran),2011,8(2):55-59. [11] Subramaniam P,Eswara U,Maheshwar Reddy KR. Effect of different types of tea on Streptococcus mutans:an in vitro study [J]. Indian J Dent Res,2012,23(1):43-48. [12] 金恩惠,吴媛媛,屠幼英. 茶黄素抑菌作用的研究[J]. 中国食品学报,2011,11(6):108-112.[13] Zhang J,Kashket S. Inhibition of salivary amylase by black and green teas and their effects on the intraoral hydrolysis of starch [J]. Caries Res,1998,32(3):233-238.[14] 林锋,姚江武. 人唾液 α-淀粉酶与红/绿茶多酚相互作用的吸附动力学研究[J]. 华西口腔医学杂志,2011,29(1):5-8. [15] Wei GX. Black tea extract and tea polyphenols inhibit growth and virulence factors of periodontal pathogens [D]. Chicago:University of Illinois,2001.[16] Zhao L,La VD,Grenier D. Antibacterial,anti-adherence,anti-protease,and anti-inflammatory properties of various tea extracts:Potential benefits for periodontal diseases [J]. J Med Food,2013,16(5):428-436.[17] Hosokawa Y,Hosokawa I,Ozaki K,et al. Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts [J]. Mol Nutr Food Res,2010,54(Suppl 2):S151-S158.[18] Tanaka M,Miyahima A. Oncostatin M,a multifunctional cytokine [M]//Reviews of physiology,biochemistry and pharmacology. Berlin Heidelberg:Springer,2004:39-52.[19] Lin SJ,Chen YL,Kuo MY,et al. Measurement of gp130 cytokines oncostatin M and IL-6 in gingival crevicular fluid of patients with chronic periodontitis [J]. Cytokine,2005,30(4):160-167.[20] Hosokawa Y,Hosokawa I,Shindo S,et al. Black tea polyphenol inhibits CXCL10 production in oncostatin M-stimulated human gingival fibroblasts [J]. Int Immunopharmacol,2011,11(6):670-674.[21] Aneja R,Odoms K,Denenberg AG,et al. Theaflavin,a black tea extract,is a novel anti-inflammatory compound [J]. Crit Care Med,2004,32(10):2097-2103. [22] Song YA,Park YL,Yoon SH,et al. Black tea polyphenol theaflavin suppresses LPS-induced ICAM-1 and VCAM-1 expression via blockage of NF-κB and JNK activation in intestinal epithelial cells [J]. Inflamm Res,2011,60(5):493-500. [23] Kim S,Joo YE. Theaflavin inhibits LPS-induced IL-6,MCP-1,and ICAM-1expression in bone marrow-derived macrophages through the blockade of NF-κB and MAPK signaling pathways [J]. Chonnam Med J,2011,47(2):104-110. [24] 龚雨顺,黄建安,刘仲华,等. 茶叶功能成份对甲硫醇的去除效果[J]. 茶叶科学,2008,28(2):111-114.[25] Masuda J,Hiroshi M,Joji F. Deodorization by used tea leaves [J]. Seikatsu Eisei,2004,48:92-96.[26] Sitheeque MA,Panagoda GJ,Yau J,et al. Antifungal activity of black tea polyphenols(catechins and theaflavins)against Candida species [J]. Chemotherapy,2009,55(3):189-196.[27] Isaacs CE,Xu W,Merz G,et al. Digallate dimers of (-)-epigallocatechin gallate inactivate herpes simplex virus [J]. Antimicrob Agents Chemother,2011,55(12):5646-5653.[28] ?uczaj W,Skrzydlewska E. Antioxidative properties of black tea [J]. Prev Med,2005,40(6):910-918.[29] Yang Z,Jie G,Dong F,et al. Radical-scavenging abilities and antioxidant properties of theaflavins and their gallate esters in H2O2-mediated oxidative damage system in the HPF-1 cells [J]. Toxicol in Vitro,2008,22(5):1250-1256.[30] Lin YL,Tsai SH,Lin-Shiau SY,et al. Theaflavin-3,3'-digallate from black tea blocks the nitric oxide synthase by down-regulating the activation of NF-kappaB in macrophages [J]. Eur J Pharmacol,1999,367(2-3):379-388.[31] Halder A,Raychowdhury R,Ghosh A,et al. Black tea(Camellia sinensis)as a chemopreventive agent in oral precancerous lesions [J]. J Environ Pathol Toxicol Oncol,2005,24(2):141-144.[32] Pal D,Banerjee S,Indra D,et al. Influence of regular black tea consumption on tobacco associated DNA damage and HPV prevalence in human oral mucosa [J]. Asian Pac J Cancer Prev,2007,8(2):263-266.[33] Pal D,Sur S,Mandal S,et al. Regular black tea habit could reduce tobacco associated ROS generation and DNA damage in oral mucosa of normal population [J]. Food Chem Toxicol,2012,50(9):2996-3003.[34] Chang YC,Chen PN,Chu SC,et al. Black tea polyphenols reverse epithelial-to-mesenchymal transition and suppress cancer invasion and proteases in human oral cancer cells [J]. J Agric Food Chem,2012,60(34):8395-8403.[35] Chandra Mohan KV,Devaraj H,Prathiba D,et al. Antiproliferative and apoptosis inducing effect of lactoferrin and black tea polyphenol combination on hamster buccal pouch carcinogenesis [J]. Biochim Biophys Acta,2006,1760(10):1536-1544.[36] Letchoumy PV,Mohan KV,Prathiba D,et al. Comparative evaluation of anti-proliferative,antiangiogenic and apoptosis inducing potential of black tea polyphenols in the hamster buccal pouch carcinogenesis model [J]. J Carcinog,2007,6:19.[37] Mikutis G,Karaköse H,Jaiswal R,et al. Phenolic promiscuity in the cell nucleus--epigallocatechingallate (EGCG) and theaflavin-3,3′-digallate from green and black tea bind to model cell nuclear structures including histone proteins,double stranded DNA and telomeric quadruplex DNA [J]. Food Funct,2013,4(2):328-337.[38] Lu J,Ho CT,Ghai G,et al. Differential effects of theaflavin monogallates on cell growth,apoptosis,and Cox-2 gene expression in cancerous versus normal cells [J]. Cancer Res,2000,60(22):6465-6471.[39] Mizuno H,Cho YY,Zhu F,et al. Theaflavin-3,3'-digallate induces epidermal growth factor receptor downregulation [J]. Mol Carcinog,2006,45(3):204-212.[40] Ohata M,Koyama Y,Suzuki T,et al. Effects of tea constituents on cell cycle progression of human leukemia U937 cells [J]. Biomed Res,2005,26(1):1-7.