Bone morphogenetic protein-2 on the invasion of HO8910 ovarian cancer cells.
MA Ying,LENG Hong-rui, ZHANG Shu-lan.
Chinese Journal of Practical Gynecology and Obstetrics ›› 2014, Vol. 30 ›› Issue (8) : 626-630.
Bone morphogenetic protein-2 on the invasion of HO8910 ovarian cancer cells.
Abstract： Objective To verify the influence of bone morphogenetic protein-2 (BMP-2) on the invasion capacity of human ovarian serous cystadenoma cell HO8910, and to determine the possible mechanism.Methods Cell adhesion experiment, cross-river experiment and matrigel-transwell assay were performed to observe the influence of BMP-2 on the invasion ability of HO8910 cells. The changes of MMP-2 and TIMP-2 in HO8910 cells following BMP-2 intervention were also detected in Sheng Jing Hospital of China Medical University between 2008 and 2009.
ovarian cancer / BMP-2 / invasion / MMP-2 / TIMP-2
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（2013-03-08收稿 2014-04-10修回）
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