康妇炎胶囊在治疗输卵管通而不畅性不孕中的临床应用

张钰a,徐国萍b,孙丽a,孙霞a

中国实用妇科与产科杂志 ›› 2015, Vol. 31 ›› Issue (7) : 672-675.

中国实用妇科与产科杂志 ›› 2015, Vol. 31 ›› Issue (7) : 672-675. DOI: 10.7504/fk2015060124
论著

康妇炎胶囊在治疗输卵管通而不畅性不孕中的临床应用

  • 张钰,徐国萍,孙丽,孙霞
作者信息 +

Clinical application of Kangfuyan capsule in the treatment of partially obstructed fallopian tube infertility.

  • ZHANG Yu,XU Guo-ping,SUN Li,SUN Xia.
Author information +
文章历史 +

摘要

目的 探讨康妇炎胶囊在治疗输卵管通而不畅性不孕中的临床应用效果。方法 2012年1月至2014年1月在天津医科大学第二医院根据子宫输卵管造影结果选择轻度输卵管通而不畅患者143例(治疗组89例和对照组54例)和重度输卵管通而不畅患者120例(治疗组77例和对照组43例)。轻度输卵管通而不畅治疗组采用输卵管通液术联合康妇炎胶囊口服,对照组仅行输卵管通液术。重度输卵管通而不畅治疗组采用宫腹腔镜再通手术联合康妇炎胶囊口服,对照组仅行宫腹腔镜再通手术。记录患者12个月内妊娠的情况并计算宫内妊娠率和异位妊娠率等指标。结果 轻度输卵管通而不畅治疗组宫内妊娠率显著高于对照组(70.8%对51.9%),差异有统计学意义(P<0.05);输卵管妊娠率显著低于对照组(1.1%对7.4%),差异有统计学意义(P<0.05);生化妊娠率两组比较(4.5%对7.4%),差异无统计学意义(P>0.05)。重度输卵管通而不畅患者治疗组宫内妊娠率显著高于对照组(37.7%对20.9%),差异有统计学意义(P<0.05);输卵管妊娠率显著低于对照组(5.2%对16.3%),差异有统计学意义(P<0.05);生化妊娠率两组比较(6.5%对9.3%),差异无统计学意义(P>0.05)。12个月后轻度输卵管通而不畅治疗组未妊娠患者的输卵管通而不畅率(26.2%对50%)和阻塞率(4.8%对22.2%)均低于对照组,差异有统计学意义(均P<0.05);重度输卵管通而不畅治疗组未妊娠患者的输卵管通而不畅率(32.1%对52.2%)和阻塞率(7.7%对21.7%)均低于对照组,差异有统计学意义(均P<0.05)。结论 康妇炎胶囊在辅助治疗输卵管通而不畅性不孕中具有良好的疗效,可以提高输卵管通而不畅性不孕患者的宫内妊娠率和再通率,同时降低输卵管妊娠率。

Abstract

Abstract: Objective To investigate therapeutic efficiency of Kangfuyan capsule on infertile patients with partially obstructed fallopian tube infertility. Methods Total 143 mild patients and 120 severe patients with partially obstructed fallopian tube were selected according to the imaging diagnosis of hysterosalpingography. Patients with mild partially obstructed fallopian tube were randomly divided into treatment group (89 cases) and control group (54 cases),and the combined therapy of hydrotubation and Kangfuyan capsule were used in treatment group,while the control group only received hydrotubation. Patients with severe partially obstructed fallopian tube were randomly divided into treatment group (77 cases) and control group (43 cases),and the combined therapy of hysteroscopy-laparoscopic surgery and Kangfuyan capsule were used in treatment group,while the control group only received hysteroscopy-laparoscopic surgery.Results The rate of intrauterine pregnancy in treatment group with mild partially obstructed fallopian tube was higher than control group(70.8% vs. 51.9%),the difference being statistically significant(P<0.05). The rate of tubal pregnancy rate was lower than control group(1.1% vs. 7.4%),the difference being statistically significant(P<0.05). There was no statistically significant difference between two groups in the rate of biochemical pregnancy (4.5% to 7.4%) (P>0.05). The intrauterine pregnancy in treatment group with severe partially obstructed fallopian tube was higher than control group(37.7% vs. 20.9%),the difference being statistically significant(P<0.05). The rate of tubal pregnancy rate was lower than control group(5.2% vs. 16.3%),the difference being statistically significant(P<0.05). There was no statistically significant difference between two groups in the rate of biochemical pregnancy (6.5% vs. 9.3%) (P>0.05). Through 12 months of follow-up, among non-pregnant patients, the rate of partially obstructed fallopian tube (26.2% vs. 50%) and completely obstructed fallopian tube(4.8% vs. 22.2%) in treatment group with mild partially obstructed fallopian tube were lower than control group, the difference being statistically significant(P<0.05);the rate of partially obstructed fallopian tube (32.1% vs. 52.2%) and completely obstructed fallopian tube(7.7% vs. 21.7%) in treatment group with severe partially obstructed fallopian tube were lower than control group, the difference being statistically significant(P<0.05).Conclusion Kangfuyan capsule has good curative effect in auxiliary treatment of partially obstructed fallopian tube,which can improve the intrauterine pregnancy and tubal recanalization rate,and reduce tubal pregnancy rate at the same time.

关键词

不孕 / 康妇炎胶囊 / 输卵管 / 通而不畅

Key words

infertility / Kangfuyan capsule / fallopian tube / partially obstructed

引用本文

导出引用
张钰a,徐国萍b,孙丽a,孙霞a. 康妇炎胶囊在治疗输卵管通而不畅性不孕中的临床应用[J]. 中国实用妇科与产科杂志. 2015, 31(7): 672-675 https://doi.org/10.7504/fk2015060124
ZHANG Yu,XU Guo-ping,SUN Li,SUN Xia.. Clinical application of Kangfuyan capsule in the treatment of partially obstructed fallopian tube infertility.[J]. Chinese Journal of Practical Gynecology and Obstetrics. 2015, 31(7): 672-675 https://doi.org/10.7504/fk2015060124
中图分类号: R711.6   

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(2015-01-25  收稿  2015-03-14  修回)


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