关键词: 木村病, 肾病综合征, 淋巴结

Abstract:

Objective　To improve the level of diagnosis and treatment of children with Kimura’s disease complicated with nephrotic syndrome. Methods　In order to understand the current pathogenesis，diagnosis and treatment of children with Kimura’s disease complicated with nephrotic syndrome，we reviewed 3 cases of  Kimura’s disease in our department from 2011 to 2015，and studied the related literature at home and abroad at the same time. Results　Kimura’s disease is a rare chronic immune inflammatory disease which mainly damaged lymph nodes，soft tissue and salivary glands. It mostly occurs in Asian people between the age of 28 and 32，especially male. At present，the cause of the disease and its pathogenesis is still unclear. Histopathology is the only way to diagnose Kimura’s disease. As the golden standard of kidney disease diagnosis，renal biopsy is a big help for the diagnosis and treatment of renal damage of Kimura’s disease. Current treatments mainly depend on medication，and generally hormone combined immune inhibitors are used. Conclusion　Kimura’s disease is a chronic disease，which is a benign lesion but easy to recur. There usually is no malignant change.

Key words: Kimura&rsquo, s disease；nephrotic syndrome；lymph node